Corn Snake Stopped Eating

I'm new to this forum, so I imagine this question has been asked before. I
have a year old corn that for a long time was eating about two small mice
every week. Prior to now she was never very active in her cage except when
ready to feed again. For the last six weeks she has been very actively
exploring her cage and looking for every opportunity to escape. And, she
refuses to eat. She seems healthy in all other ways, just will not eat.
Should I be concerned? Thanks for all of your feedback.